Tolerance to Infectious Diseases in Animals Disentangling Genetic Variation for Resistance And
نویسنده
چکیده
www.sciencemag.org (this information is current as of November 5, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/318/5851/812 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/318/5851/812/DC1 can be found at: Supporting Online Material http://www.sciencemag.org/cgi/content/full/318/5851/812#otherarticles , 4 of which can be accessed for free: cites 27 articles This article http://www.sciencemag.org/cgi/collection/immunology Immunology : subject collections This article appears in the following http://www.sciencemag.org/about/permissions.dtl in whole or in part can be found at: this article permission to reproduce of this article or about obtaining reprints Information about obtaining
منابع مشابه
Disentangling genetic variation for resistance and tolerance to infectious diseases in animals.
Hosts can in principle employ two different strategies to defend themselves against parasites: resistance and tolerance. Animals typically exhibit considerable genetic variation for resistance (the ability to limit parasite burden). However, little is known about whether animals can evolve tolerance (the ability to limit the damage caused by a given parasite burden). Using rodent malaria in lab...
متن کاملThe h-index and self-citations.
References 1 Restif, O. and Koella, J.C. (2004) Concurrent evolution of resistance and tolerance to pathogens. Am. Nat. 164, E90–E102 2 Miller, M.R. et al. (2005) The evolution of host resistance: tolerance and control as distinct strategies. J. Theor. Biol. 236, 198–207 3 Fineblum, W.L. and Rausher, M.D. (1995) Tradeoff between resistance and tolerance to herbivore damage in a morning glory. N...
متن کاملGenetic Variation in Disease Resistance among Farm Animals
This background study paper reviews the results of scientific investigations involving genetic control mechanisms for resistance/tolerance in farm animals to specific viral, bacterial, parasitic and prion diseases. The paper presents the most prominent documented examples for resistance/tolerance in cows, sheep and goats, pigs and poultry. The importance of genetically heterogeneous populations...
متن کاملDecomposing health: tolerance and resistance to parasites in animals.
Plant biologists have long recognized that host defence against parasites and pathogens can be divided into two conceptually different components: the ability to limit parasite burden (resistance) and the ability to limit the harm caused by a given burden (tolerance). Together these two components determine how well a host is protected against the effects of parasitism. This distinction is usef...
متن کاملGenetic Diversity and Drug Resistance of Helicobacter pylori Strains in Isfahan, Iran
Objective(s) Resistance to antimicrobial agents, particularly metronidazole and clarithromycin, is frequently observed in Helicobacter pylori and may be associated with treatment failure. This resistance rate varies according to the population studied. The aim of this study was to assess the pattern of antimicrobial resistance of H. pylori isolates from dyspeptic patients in Isfahan. Material...
متن کامل